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Uricase is an enzyme that catalyzes the conversion or uric acid to allantoin. Uric acid is

an acidic waste product that your body passes through urine. It is a normal byproduct of the breakdown of foods that contain purines. Normally, the kidneys filter out uric acid from your blood; if too much builds up, it can lower the pH of your blood and urine and lead to a painful joint condition called gout and other complications. The reason I chose uricase is because it monitors the uric acid levels in our body. Interestingly, humans have naturally selected to terminate uricase. Because of the absence of uricase in humans, we may go through many complications caused by uric acid build up. Scientists are studying why natural selection would allow the accumulation of uric acid even though there are psychological complications of crystalized monosodium urate acutely causing liver and kidney damage or chronically causing gout.

Function

Disease

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.