5ooh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex== | |
| - | + | <StructureSection load='5ooh' size='340' side='right' caption='[[5ooh]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ooh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OOH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OOH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ZZ:Erythrosin'>9ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ooh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ooh OCA], [http://pdbe.org/5ooh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ooh RCSB], [http://www.ebi.ac.uk/pdbsum/5ooh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ooh ProSAT]</span></td></tr> |
| - | [[Category: Pereira, P | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/BLVRB_HUMAN BLVRB_HUMAN]] Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.<ref>PMID:10620517</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Manso, J A]] | ||
| + | [[Category: Pereira, P J.B]] | ||
| + | [[Category: Biliverdin reductase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 05:00, 8 March 2018
Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex
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