5vxn

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'''Unreleased structure'''
 
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The entry 5vxn is ON HOLD until sometime in the future
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==Structure of two RcsB dimers bound to two parallel DNAs.==
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<StructureSection load='5vxn' size='340' side='right' caption='[[5vxn]], [[Resolution|resolution]] 3.38&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5vxn]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXN FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxn OCA], [http://pdbe.org/5vxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxn RCSB], [http://www.ebi.ac.uk/pdbsum/5vxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxn ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RCSB_ECOLI RCSB_ECOLI]] Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. The system regulates expression of numerous genes, including genes involved in colanic acid capsule synthesis, biofilm formation, cell division and outer membrane proteins synthesis. Also involved, with GadE, in control of glutamate-dependent acid resistance, and, with BglJ, in derepression of the cryptic bgl operon. The RcsB-BglJ activity is probably independent of RcsB phosphorylation.[HAMAP-Rule:MF_00981]<ref>PMID:10702265</ref> <ref>PMID:11309126</ref> <ref>PMID:11566985</ref> <ref>PMID:13129944</ref> <ref>PMID:1597415</ref> <ref>PMID:20189963</ref> <ref>PMID:20952573</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Anderson, W F]]
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[[Category: Structural genomic]]
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[[Category: Filippova, E V]]
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[[Category: Minasov, G]]
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[[Category: Pshenychnyi, S]]
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[[Category: Csgid]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Dna-binding protein]]
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[[Category: Fixj/narl]]
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[[Category: Rcs phosphorelay]]
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[[Category: Response regulator]]

Revision as of 05:02, 8 March 2018

Structure of two RcsB dimers bound to two parallel DNAs.

5vxn, resolution 3.38Å

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