5xm0
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4== |
| - | + | <StructureSection load='5xm0' size='340' side='right' caption='[[5xm0]], [[Resolution|resolution]] 2.87Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xm0]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XM0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xm0 OCA], [http://pdbe.org/5xm0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xm0 RCSB], [http://www.ebi.ac.uk/pdbsum/5xm0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xm0 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/H2B3A_MOUSE H2B3A_MOUSE]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H2A1B_MOUSE H2A1B_MOUSE]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Horikoshi, N]] | ||
| + | [[Category: Kurumizaka, H]] | ||
| + | [[Category: Taguchi, H]] | ||
| + | [[Category: Chromatin]] | ||
| + | [[Category: Dna-protein complex]] | ||
| + | [[Category: Nucleosome]] | ||
| + | [[Category: Structural protein-dna complex]] | ||
Revision as of 05:05, 8 March 2018
The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4
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