5m4h
From Proteopedia
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| <StructureSection load='5m4h' size='340' side='right' caption='[[5m4h]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='5m4h' size='340' side='right' caption='[[5m4h]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5m4h]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M4H FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5m4h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M4H FirstGlance]. <br> | 
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7FX:[2,4-BIS(OXIDANYL)PHENYL]-[(7~{S})-7-(TRIFLUOROMETHYL)-6,7-DIHYDRO-5~{H}-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]METHANONE'>7FX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7FX:[2,4-BIS(OXIDANYL)PHENYL]-[(7~{S})-7-(TRIFLUOROMETHYL)-6,7-DIHYDRO-5~{H}-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]METHANONE'>7FX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m4h OCA], [http://pdbe.org/5m4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m4h RCSB], [http://www.ebi.ac.uk/pdbsum/5m4h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m4h ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m4h OCA], [http://pdbe.org/5m4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m4h RCSB], [http://www.ebi.ac.uk/pdbsum/5m4h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m4h ProSAT]</span></td></tr> | ||
| </table> | </table> | ||
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| </div> | </div> | ||
| <div class="pdbe-citations 5m4h" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5m4h" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
| == References == | == References == | ||
| <references/> | <references/> | ||
| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| [[Category: Baker, L M]] | [[Category: Baker, L M]] | ||
| [[Category: Brough, P]] | [[Category: Brough, P]] | ||
Revision as of 06:08, 8 March 2018
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
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Categories: Human | Baker, L M | Brough, P | Surgenor, A | Cancer | Fragment screening | Hsp90 | Kinase inhibitor | Off-rate screening | Pdhk | Pdk1 | Pdk2 | Pdk3 | Pdk4 | Signaling protein | Spr
