Alice Clark/ATPsynthase

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3. Releasing the newly made ATP
3. Releasing the newly made ATP
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ATP synthase is shown here to the right in 3D with each protein shown a different colour, using the Jmol viewer within [http://proteopedia.org/wiki/index.php/Main_Page Proteopedia].
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ATP synthase is shown here to the right in 3D with each protein shown a different colour. You are viewing the molecular model using the Jmol viewer within [http://proteopedia.org/wiki/index.php/Main_Page Proteopedia].
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''''Have a go yourself now ==>''''
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'''Have a go yourself now ==>'''
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'''The ATP synthase molecule'''
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'''Exploring the ATP synthase molecule'''
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ATP synthase is built up of different groups of proteins: the F0, the F1 and the axel - each with a important role.
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ATP synthase is built up of different groups of proteins: the F0, the F1, the stator and the axel - each group with a important role.
The <scene name='78/781973/Alpha-beta/1'>F1 motor</scene> contains alpha (shown in light blue) and beta (shown in dark blue) protein chains. It also binds the adenosine diphosphate (ADP) molecules and the adenosine triphosphate (ATP) <scene name='78/781973/Atpandadp/1'>binding sites</scene>. See if you can zoom in on the ATP identify how many phosphates (atoms shown in orange) are found.
The <scene name='78/781973/Alpha-beta/1'>F1 motor</scene> contains alpha (shown in light blue) and beta (shown in dark blue) protein chains. It also binds the adenosine diphosphate (ADP) molecules and the adenosine triphosphate (ATP) <scene name='78/781973/Atpandadp/1'>binding sites</scene>. See if you can zoom in on the ATP identify how many phosphates (atoms shown in orange) are found.
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'''Q1: Where is the F1 region located within the ATP synthase, and what is its role?'''
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'''Q1: How many chains makeup the F1 region, and what is it's role in generating ATP?'''
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<scene name='78/781973/F0/1'>The F0</scene> is a circular rotor that is formed of alpha helices that sit in the mitochondrial membrane. The hydrogen ions travel around the circular F0 motor, and turning the rotor in the process, much like a water wheel. The hydrogens are passed alone a chain of aspartic acid residues (amino acids) in the F0 motor, and then transferred to an arginine amino acid. The arginine passes the hydrogen to the rotor, which turns all the way around. Then the hydrogen is then passed to the opposite side of the membrane.
<scene name='78/781973/F0/1'>The F0</scene> is a circular rotor that is formed of alpha helices that sit in the mitochondrial membrane. The hydrogen ions travel around the circular F0 motor, and turning the rotor in the process, much like a water wheel. The hydrogens are passed alone a chain of aspartic acid residues (amino acids) in the F0 motor, and then transferred to an arginine amino acid. The arginine passes the hydrogen to the rotor, which turns all the way around. Then the hydrogen is then passed to the opposite side of the membrane.
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Click '>here</scene> for a view where the different components are coloured differently? See how many you can identify
 
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'''Q4: What are the two key amino acid that bind the hydrogen's in the ATP generation?'''
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ATP synthase is an example of a molecular motor.
ATP synthase is an example of a molecular motor.
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Use the Structure to answer the questions below.
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Revision as of 15:00, 10 March 2018

ATP Synthase

ATP Synthase (PDB entry 5lqz)

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Proteopedia Page Contributors and Editors (what is this?)

Alice Clark

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