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Aldehyde dehydrogenase

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Line 47: Line 47:
**[[4x4l]] - hALDH1 + NAD derivative + inhibitor<br />
**[[4x4l]] - hALDH1 + NAD derivative + inhibitor<br />
**[[1ht0]] – hALDH1 γ subunit (mutant) + Zn + NAD
**[[1ht0]] – hALDH1 γ subunit (mutant) + Zn + NAD
 +
 +
*ALDH class 1 A (retinal dehydrogenase)
 +
 +
**[[5l2m]], [[5l2n]], [[5l2o]] – hRALDH1 + inhibitor<br />
 +
**[[5tei]] – hRALDH1 + NAD + inhibitor<br />
 +
**[[6alj]], [[6b5g]], [[6b5h]], [[6b5i]] – hRALDH2 + NAD + inhibitor<br />
 +
**[[5fhz]] – hRALDH3 + NAD + retinol<br />
*ALDH class 2
*ALDH class 2
Line 69: Line 76:
**[[1o01]] - hALDH2 residues 18-517 + NADH + aldehyde<br />
**[[1o01]] - hALDH2 residues 18-517 + NADH + aldehyde<br />
**[[4fqf]] - hALDH2 residues 18-517 + NAD + NO2<br />
**[[4fqf]] - hALDH2 residues 18-517 + NAD + NO2<br />
-
**[[4fr8]] - hALDH2 residues 18-517 (mutant) + NAD + ADP + nitroglycerin
+
**[[4fr8]] - hALDH2 residues 18-517 (mutant) + NAD + ADP + nitroglycerin<br />
 +
**[[5l13]] – hALDH2 + inhibitor<br />
*ALDH class 3
*ALDH class 3
Line 78: Line 86:
**[[4h80]] - hALDH3A1 (mutant) + inhibitor<br />
**[[4h80]] - hALDH3A1 (mutant) + inhibitor<br />
**[[4qgk]] – hALDH3A2 + ligand<br />
**[[4qgk]] – hALDH3A2 + ligand<br />
 +
**[[5myp]] – TbALDH – ''Trypanosoma brucei''<br />
 +
**[[5nno]] – TbALDH + NAD + inhibitor <br />
*NAD-dependent ALDH
*NAD-dependent ALDH
Line 101: Line 111:
**[[4qf6]], [[5gt6]] – BcALDH – ''Bacillus cereus''<br />
**[[4qf6]], [[5gt6]] – BcALDH – ''Bacillus cereus''<br />
**[[4qet]] – BcALDH (mutant)<br />
**[[4qet]] – BcALDH (mutant)<br />
 +
**[[5uju]] - BmALDH – ''Burkholderia multivorans''<br />
*NAD-dependent ALDH binary complexes
*NAD-dependent ALDH binary complexes
Line 121: Line 132:
**[[4i3u]] – SmALDH + phosphonoacetaldehyde<br />
**[[4i3u]] – SmALDH + phosphonoacetaldehyde<br />
**[[5gtk]] – BcALDH + NAD<br />
**[[5gtk]] – BcALDH + NAD<br />
 +
**[[5jfl]] – RpALDH + NAD – ''Rhodopseudomonas palustris''<br />
 +
**[[5jfn]] – RpALDH + CoA <br />
*NAD-dependent ALDH ternary complexes
*NAD-dependent ALDH ternary complexes
Line 129: Line 142:
**[[4i3v]], [[4i3w]] – SmALDH + aldehyde derivative + NAD<br />
**[[4i3v]], [[4i3w]] – SmALDH + aldehyde derivative + NAD<br />
**[[4i3x]] – SmALDH + phosphonoacete + NAD<br />
**[[4i3x]] – SmALDH + phosphonoacete + NAD<br />
 +
**[[5jfm]] – RpALDH + CoA + propionyl-CoA<br />
*NADP-dependent ALDH
*NADP-dependent ALDH
Line 155: Line 169:
**[[4h73]], [[4nmj]], [[4nmk]], [[5f2c]], [[5exf]], [[5euy]], [[5ekc]], [[5ek6]] - PfALDH + NADP <br />
**[[4h73]], [[4nmj]], [[4nmk]], [[5f2c]], [[5exf]], [[5euy]], [[5ekc]], [[5ek6]] - PfALDH + NADP <br />
**[[5kf0]] - ALDH + NADP – ''Burkholderia vietnamiensis''<br />
**[[5kf0]] - ALDH + NADP – ''Burkholderia vietnamiensis''<br />
-
**[[5jry]] - ALDH + NADP – ''Burkholderia multivorans''<br />
+
**[[5jry]] - BmALDH + NADP <br />
**[[5j6b]] - BtALDH + NADP <br />
**[[5j6b]] - BtALDH + NADP <br />
**[[5gtl]] – BcALDH + NADP<br />
**[[5gtl]] – BcALDH + NADP<br />
*NADP-dependent ALDH ternary complexes
*NADP-dependent ALDH ternary complexes
- 
**[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR />
**[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR />
**[[2vro]] – BxALDH + NADP + alcohol <br />
**[[2vro]] – BxALDH + NADP + alcohol <br />
 +
 +
*Indole-3-ALDH
 +
 +
**[[5iuu]] – PsIALDH – ''Pseudomonas syringae''<br />
 +
**[[5iuv]] – PsIALDH + NAD<br />
 +
**[[5iuw]] – PsIALDH + NAD + indole acetate<br />
*NAD-dependent glyceraldehydes-3-phosphate dehydrogenase
*NAD-dependent glyceraldehydes-3-phosphate dehydrogenase
Line 246: Line 265:
**[[4dng]] – ALDH – ''Bacillus subtilis''<br />
**[[4dng]] – ALDH – ''Bacillus subtilis''<br />
**[[3my7]] – ALDH – ''Vibrio parahaemolyticus''<br />
**[[3my7]] – ALDH – ''Vibrio parahaemolyticus''<br />
 +
**[[4qyj]] - PpALDH<br />
 +
**[[5mz5]] – PhpALDH 21 – ''Physcomitrella patens''<br />
 +
**[[5mz8]] – PhpALDH 21 + succinate<br />
 +
**[[5n5s]] – PhpALDH 21 + NADP<br />
*Antiquitin
*Antiquitin

Revision as of 10:31, 11 March 2018

Aldehyde hydrogenase class 1 tetramer complex with NAD, dithiothreitol and dimercaptobutane-diol, 1o9j

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3D Structures of Aldehyde dehydrogenase

Updated on 11-March-2018

References

  1. ↑ Keller, Markus A.; Zander, Ulrich; Fuchs, Julian E.; Kreutz, Christoph; Watschinger, Katrin et al. (2014). A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Nature Communications vol. 5.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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