5x8a

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'''Unreleased structure'''
 
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The entry 5x8a is ON HOLD until Paper Publication
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==Crystal structure of ATP bound thymidylate kinase from thermus thermophilus HB8==
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<StructureSection load='5x8a' size='340' side='right' caption='[[5x8a]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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Authors: Chaudhary, S.K., Jeyakanthan, J., Sekar, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5x8a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X8A FirstGlance]. <br>
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Description: Crystal structure of ATP bound thymidylate kinase from thermus thermophilus HB8
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x86|5x86]], [[5x8b|5x8b]], [[5x8c|5x8c]], [[5x8d|5x8d]], [[5x8j|5x8j]], [[5x8k|5x8k]], [[5x8v|5x8v]], [[5x98|5x98]], [[5x99|5x99]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8a OCA], [http://pdbe.org/5x8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8a RCSB], [http://www.ebi.ac.uk/pdbsum/5x8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8a ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
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__TOC__
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</StructureSection>
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[[Category: DTMP kinase]]
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[[Category: Chaudhary, S K]]
[[Category: Jeyakanthan, J]]
[[Category: Jeyakanthan, J]]
[[Category: Sekar, K]]
[[Category: Sekar, K]]
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[[Category: Chaudhary, S.K]]
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[[Category: Nucleotide monophosphate kinase]]
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[[Category: Transferase]]

Revision as of 06:25, 14 March 2018

Crystal structure of ATP bound thymidylate kinase from thermus thermophilus HB8

5x8a, resolution 2.51Å

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