5xal

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'''Unreleased structure'''
 
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The entry 5xal is ON HOLD until Paper Publication
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==Y99F mutant of Thermus thermophilus HB8 thymidylate kinase==
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<StructureSection load='5xal' size='340' side='right' caption='[[5xal]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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Authors: Chaudhary, S.K., Jeyakanthan, J., Sekar, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5xal]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XAL FirstGlance]. <br>
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Description: Y99F mutant of Thermus thermophilus HB8 thymidylate kinase
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xak|5xak]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xal OCA], [http://pdbe.org/5xal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xal RCSB], [http://www.ebi.ac.uk/pdbsum/5xal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xal ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
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__TOC__
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</StructureSection>
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[[Category: DTMP kinase]]
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[[Category: Chaudhary, S K]]
[[Category: Jeyakanthan, J]]
[[Category: Jeyakanthan, J]]
[[Category: Sekar, K]]
[[Category: Sekar, K]]
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[[Category: Chaudhary, S.K]]
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[[Category: Nucleotide monophosphate kinase]]
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[[Category: Transferase]]

Revision as of 06:26, 14 March 2018

Y99F mutant of Thermus thermophilus HB8 thymidylate kinase

5xal, resolution 1.84Å

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