6ffn
From Proteopedia
(Difference between revisions)
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<StructureSection load='6ffn' size='340' side='right' caption='[[6ffn]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='6ffn' size='340' side='right' caption='[[6ffn]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6ffn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFN FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6ffn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hrv-2 Hrv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFN FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8K:~{N}-[(5~{S},8~{S},11~{S},15~{R})-8-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-2,7,10,14-tetrakis(oxidanylidene)-1,6,9,13-tetrazabicyclo[13.3.0]octadecan-11-yl]-5-methyl-1,2-oxazole-3-carboxamide'>D8K</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8K:~{N}-[(5~{S},8~{S},11~{S},15~{R})-8-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-2,7,10,14-tetrakis(oxidanylidene)-1,6,9,13-tetrazabicyclo[13.3.0]octadecan-11-yl]-5-methyl-1,2-oxazole-3-carboxamide'>D8K</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffn OCA], [http://pdbe.org/6ffn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffn RCSB], [http://www.ebi.ac.uk/pdbsum/6ffn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffn OCA], [http://pdbe.org/6ffn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffn RCSB], [http://www.ebi.ac.uk/pdbsum/6ffn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffn ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 6ffn" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6ffn" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[3C protease|3C protease]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Hrv-2]] | ||
[[Category: Farady, C]] | [[Category: Farady, C]] | ||
[[Category: Wiesmann, C]] | [[Category: Wiesmann, C]] |
Revision as of 07:05, 14 March 2018
Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors
|
Categories: Hrv-2 | Farady, C | Wiesmann, C | 3c protease | Hydrolase | Inhibitor | Rhinovirus