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5nnh
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==KSHV uracil-DNA glycosylase, apo form== | |
| - | + | <StructureSection load='5nnh' size='340' side='right' caption='[[5nnh]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nnh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NNH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5nn7|5nn7]], [[5nnu|5nnu]]</td></tr> |
| - | [ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil-DNA_glycosylase Uracil-DNA glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.27 3.2.2.27] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nnh OCA], [http://pdbe.org/5nnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nnh RCSB], [http://www.ebi.ac.uk/pdbsum/5nnh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nnh ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q76RG8_HHV8 Q76RG8_HHV8]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.[HAMAP-Rule:MF_04046] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Uracil-DNA glycosylase]] | ||
[[Category: Bagneris, C]] | [[Category: Bagneris, C]] | ||
[[Category: Barrett, T]] | [[Category: Barrett, T]] | ||
| + | [[Category: Cole, A R]] | ||
| + | [[Category: Earl, C]] | ||
| + | [[Category: Savva, R]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Uracil-dna glycosylase]] | ||
Revision as of 07:30, 21 March 2018
KSHV uracil-DNA glycosylase, apo form
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