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5wyp
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus== | |
| - | + | <StructureSection load='5wyp' size='340' side='right' caption='[[5wyp]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wyp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WYP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x10|5x10]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyp OCA], [http://pdbe.org/5wyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wyp RCSB], [http://www.ebi.ac.uk/pdbsum/5wyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyp ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPO3B_CAUCR DPO3B_CAUCR]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[UniProtKB:P0A988] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Jiang, X]] | ||
| + | [[Category: Li, X]] | ||
| + | [[Category: Teng, M]] | ||
[[Category: Zhang, L]] | [[Category: Zhang, L]] | ||
| - | [[Category: | + | [[Category: Dna binding]] |
| - | [[Category: | + | [[Category: Homodimer]] |
| - | [[Category: | + | [[Category: Protein binding]] |
| + | [[Category: Transferase]] | ||
Revision as of 07:33, 21 March 2018
Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus
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Categories: Jiang, X | Li, X | Teng, M | Zhang, L | Dna binding | Homodimer | Protein binding | Transferase
