User:Cory A. Wuerch/Sandbox 1
From Proteopedia
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=Structure= | =Structure= | ||
Hrp1 is composed of two RNP-type RNA-binding domains (RBDs) arranged in tandem. | Hrp1 is composed of two RNP-type RNA-binding domains (RBDs) arranged in tandem. | ||
| - | [[Image:Hrp1 structure for protopedia.png| | + | [[Image:Hrp1 structure cropped for protopedia.png|350 px|left|thumb|Figure 1: Cartoon representation of the Hrp1-PEE complex. The RNA is shown as a stick model and is colored by element. Notice the interface between the ß-sheets of Hrp1 and the RNA.]] |
==Crucial Interactions== | ==Crucial Interactions== | ||
The interface between Hrp1 and its target RNA sequence is dominated by interactions between key aromatic residues and RNA bases. Hydrophilic residues of Hrp1 provide base specificity through hydrogen bonding. Most of the key residues that interact with the RNA can be found in the ß-sheet region of Hrp1; however, loops and the interdomain linker are also essential for Hrp1-RNA recognition. | The interface between Hrp1 and its target RNA sequence is dominated by interactions between key aromatic residues and RNA bases. Hydrophilic residues of Hrp1 provide base specificity through hydrogen bonding. Most of the key residues that interact with the RNA can be found in the ß-sheet region of Hrp1; however, loops and the interdomain linker are also essential for Hrp1-RNA recognition. | ||
Revision as of 22:24, 26 March 2018
Contents |
Introduction
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Hrp1 is a polyadenylation factor found in Saccharomyces cervisiae (yeast).
Structure
Hrp1 is composed of two RNP-type RNA-binding domains (RBDs) arranged in tandem.
Crucial Interactions
The interface between Hrp1 and its target RNA sequence is dominated by interactions between key aromatic residues and RNA bases. Hydrophilic residues of Hrp1 provide base specificity through hydrogen bonding. Most of the key residues that interact with the RNA can be found in the ß-sheet region of Hrp1; however, loops and the interdomain linker are also essential for Hrp1-RNA recognition.
Relevance
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
