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6cnh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human PRPF4B in complex with Rebastinib== | |
| - | + | <StructureSection load='6cnh' size='340' side='right' caption='[[6cnh]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CNH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [http://pdbe.org/6cnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [http://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [ | + | == Function == |
| - | [ | + | [[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. |
| - | [[ | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Arruda, P]] | [[Category: Arruda, P]] | ||
| - | [[Category: | + | [[Category: Counago, R M]] |
| - | [[Category: | + | [[Category: Edwards, A M]] |
| - | [[Category: Ramos, P | + | [[Category: Elkins, J M]] |
| - | [[Category: | + | [[Category: Fala, A M]] |
| + | [[Category: Gileadi, O]] | ||
| + | [[Category: Godoi, P H.C]] | ||
| + | [[Category: Guimaraes, C R.W]] | ||
| + | [[Category: Massirer, K B]] | ||
| + | [[Category: Ramos, P Z]] | ||
| + | [[Category: Righetto, G L]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Salmazo, A P.T]] | ||
| + | [[Category: Santiago, A S]] | ||
| + | [[Category: Silva, P N.B]] | ||
| + | [[Category: Dcc2036]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:40, 28 March 2018
Human PRPF4B in complex with Rebastinib
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Categories: Non-specific serine/threonine protein kinase | Arruda, P | Counago, R M | Edwards, A M | Elkins, J M | Fala, A M | Gileadi, O | Godoi, P H.C | Guimaraes, C R.W | Massirer, K B | Ramos, P Z | Righetto, G L | Structural genomic | Salmazo, A P.T | Santiago, A S | Silva, P N.B | Dcc2036 | Inhibitor | Kinase | Sgc | Transferase
