6fia
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human LINE-1 ORF1p coiled coil domain== | |
| - | + | <StructureSection load='6fia' size='340' side='right' caption='[[6fia]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fia]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yko|2yko]], [[2ykp|2ykp]], [[2ykq|2ykq]], [[2w7a|2w7a]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fia OCA], [http://pdbe.org/6fia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fia RCSB], [http://www.ebi.ac.uk/pdbsum/6fia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fia ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LORF1_HUMAN LORF1_HUMAN]] Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.<ref>PMID:11158327</ref> <ref>PMID:21937507</ref> <ref>PMID:8945518</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Khazina, E]] | ||
| + | [[Category: Weichenrieder, O]] | ||
| + | [[Category: Coiled coil]] | ||
| + | [[Category: Genome evolution]] | ||
| + | [[Category: Nucleic acid chaperone]] | ||
| + | [[Category: Retrotransposition]] | ||
| + | [[Category: Rna binding protein]] | ||
| + | [[Category: Rnp]] | ||
Revision as of 06:42, 28 March 2018
Structure of the human LINE-1 ORF1p coiled coil domain
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