This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
RecG protein
From Proteopedia
Alisa Ferofontov (Talk | contribs)
(New page: '''RecG''' The RecG protein of Escherichia coli is a Superfamily 2 (SF2) branched-DNA-specific helicase which promotes rescue of damaged replication forks by catalysing their unwinding ...)
Next diff →
Revision as of 10:35, 29 March 2018
RecG
The RecG protein of Escherichia coli is a Superfamily 2 (SF2) branched-DNA-specific helicase which promotes rescue of damaged replication forks by catalysing their unwinding and conversion to Holliday junctions. A single RecG monomer unwinds two DNA duplexes; the leading strand duplex and the lagging strand duplex and then reanneal the parental and the newly synthetized strands. This mechanism of repair is ATP-dependent and does not require DNA double strand break. RecG works synergistically with the RuvABC repair system[1].
Reference:- ↑ Singleton, M. R., Scaife, S. & Wigley, D. B. Structural analysis of DNA replication fork reversal by RecG. Cell 107, 79–89 (2001)
