5yve
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator== | |
| - | + | <StructureSection load='5yve' size='340' side='right' caption='[[5yve]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yve]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YVE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AF9:5-[2,4-bis(azanyl)pyrimidin-5-yl]oxy-2-methoxy-4-propan-2-yl-benzenesulfonamide'>AF9</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yve OCA], [http://pdbe.org/5yve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yve RCSB], [http://www.ebi.ac.uk/pdbsum/5yve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yve ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/P2RX3_HUMAN P2RX3_HUMAN]] Receptor for ATP that acts as a ligand-gated ion channel. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hattori, M]] | ||
| + | [[Category: Wang, Y]] | ||
| + | [[Category: Atp]] | ||
| + | [[Category: Ion channel]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 05:56, 4 April 2018
Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator
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