Casein kinase
From Proteopedia
(Difference between revisions)
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**[[2izr]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]] - hCK1-γ3 + inhibitor<br /> | **[[2izr]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]] - hCK1-γ3 + inhibitor<br /> | ||
**[[3uys]], [[5ih4]] – hCK1-δ<br /> | **[[3uys]], [[5ih4]] – hCK1-δ<br /> | ||
| - | **[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]], [[5ih5]], [[5ih6]], [[4tn6]] – hCK1-δ + inhibitor<br /> | + | **[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]], [[5ih5]], [[5ih6]], [[4tn6]], [[5mqv]] – hCK1-δ + inhibitor<br /> |
**[[4tw9]], [[4twc]] – hCK1-δ (mutant) + inhibitor<br /> | **[[4tw9]], [[4twc]] – hCK1-δ (mutant) + inhibitor<br /> | ||
**[[1cki]] – rCK1-δ (mutant) – rat<br /> | **[[1cki]] – rCK1-δ (mutant) – rat<br /> | ||
**[[1ckj]] - rCK1-δ (mutant) + WO4<br /> | **[[1ckj]] - rCK1-δ (mutant) + WO4<br /> | ||
| - | **[[4jjr]] - | + | **[[4jjr]] - moCK1-δ - mouse<br /> |
| + | **[[5x17]] - moCK1-δ + ADP<br /> | ||
**[[4hok]] - hCK1-ε <br /> | **[[4hok]] - hCK1-ε <br /> | ||
| - | **[[4hni]] - hCK1-ε + inhibitor<br /> | + | **[[4hni]], [[5w4w]] - hCK1-ε + inhibitor<br /> |
**[[1csn]] – yCK1 + MgATP – fission yeast<br /> | **[[1csn]] – yCK1 + MgATP – fission yeast<br /> | ||
**[[2csn]], [[1eh4]] – yCK1 catalytic domain + inhibitor | **[[2csn]], [[1eh4]] – yCK1 catalytic domain + inhibitor | ||
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*CK2 catalytic subunit | *CK2 catalytic subunit | ||
| - | **[[1pjk]], [[3at2]], [[3q04]], [[3qa0]], [[3war]], [[3ofm]] - hCK2 <br /> | + | **[[1pjk]], [[3at2]], [[3q04]], [[3qa0]], [[3war]], [[3ofm]], [[5t1h]] - hCK2 <br /> |
**[[1na7]], [[3fwq]], [[3juh]], [[5cu6]], [[5cvg]] - hCK2 (mutant)<br /> | **[[1na7]], [[3fwq]], [[3juh]], [[5cu6]], [[5cvg]] - hCK2 (mutant)<br /> | ||
**[[3axw]], [[3r0t]], [[3u4u]] – hCK2 + inhibitor<br /> | **[[3axw]], [[3r0t]], [[3u4u]] – hCK2 + inhibitor<br /> | ||
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**[[3u9c]] – hCK2 + resorufin<br /> | **[[3u9c]] – hCK2 + resorufin<br /> | ||
**[[2pvr]] - hCK2 + sulfate<br /> | **[[2pvr]] - hCK2 + sulfate<br /> | ||
| - | **[[1j91]], [[4rlk]] - mCK2 + ATP competitive inhibitor - maize | + | **[[1j91]], [[4rlk]], [[5ts8]] - mCK2 + ATP competitive inhibitor - maize |
**[[1lp4]], [[1daw]], [[1day]] - mCK2 + Mg-AMPPNP | **[[1lp4]], [[1daw]], [[1day]] - mCK2 + Mg-AMPPNP | ||
**[[3nsz]], [[3wow]] - hCK2 + AMPPN<br /> | **[[3nsz]], [[3wow]] - hCK2 + AMPPN<br /> | ||
| - | **[[3w8l]] - hCK2 (mutant) + inositol hexakisphosphate<br /> | + | **[[3w8l]], [[5cvh]] - hCK2 (mutant) + inositol hexakisphosphate<br /> |
**[[4dgm]] - mCK2 + apigenin<br /> | **[[4dgm]] - mCK2 + apigenin<br /> | ||
**[[4dgn]] - mCK2 + luteolin<br /> | **[[4dgn]] - mCK2 + luteolin<br /> | ||
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**[[1m2p]], [[1m2q]], [[1m2r]], [[1om1]], [[2oxd]], [[2oxx]], [[2oxy]], [[2qc6]], [[2pvh]], [[3fl5]], [[3kxg]], [[3kxh]], [[3kxm]], [[3kxn]], [[3pvg]], [[3pwd]] - mCK2 + inhibitor | **[[1m2p]], [[1m2q]], [[1m2r]], [[1om1]], [[2oxd]], [[2oxx]], [[2oxy]], [[2qc6]], [[2pvh]], [[3fl5]], [[3kxg]], [[3kxh]], [[3kxm]], [[3kxn]], [[3pvg]], [[3pwd]] - mCK2 + inhibitor | ||
| - | **[[3e3b]], [[2zjw]], [[3h30]], [[3mb6]], [[3mb7]], [[3nga]], [[3rps]], [[3pe1]], [[3pe2]], [[3amy]], [[3at3]], [[3at4]], [[4anm]], [[4grb]], [[4gub]], [[3axw]], [[3r0t]], [[3u4u]], [[3owj]], [[3owk]], [[3owl]], [[3wik]], [[3wil]], [[5cqw]], [[5cqu]], [[4kwp]], [[4rll]], [[5m44]], [[5m4c]], [[5m4f]], [[5m4i]], [[5h8b]], [[5h8e]], [[5h8g]], [[5b0x]], [[4ub7]], [[4uba]] - hCK2 + inhibitor<br /> | + | **[[3e3b]], [[2zjw]], [[3h30]], [[3mb6]], [[3mb7]], [[3nga]], [[3rps]], [[3pe1]], [[3pe2]], [[3amy]], [[3at3]], [[3at4]], [[4anm]], [[4grb]], [[4gub]], [[3axw]], [[3r0t]], [[3u4u]], [[3owj]], [[3owk]], [[3owl]], [[3wik]], [[3wil]], [[5cqw]], [[5cqu]], [[4kwp]], [[4rll]], [[5m44]], [[5m4c]], [[5m4f]], [[5m4i]], [[5h8b]], [[5h8e]], [[5h8g]], [[5b0x]], [[4ub7]], [[4uba]], [[5omy]], [[5nqc]], [[5n9n]], [[5n9l]], [[5n1v]], [[5kwh]], [[5ku8]] - hCK2 + inhibitor<br /> |
| - | **[[5m4u]], [[5m56]], [[5clp]], [[5cs6]], [[5csh]], [[5csp]], [[5csv]], [[5ct0]], [[5ctp]], [[5cu0]], [[5cu2]], [[5cu3]], [[5cu4]], [[5cvf]], [[5cx9]] - hCK2 (mutant) + inhibitor<br /> | + | **[[5m4u]], [[5m56]], [[5clp]], [[5cs6]], [[5csh]], [[5csp]], [[5csv]], [[5ct0]], [[5ctp]], [[5cu0]], [[5cu2]], [[5cu3]], [[5cu4]], [[5cvf]], [[5cx9]], [[6ehk]], [[6ehu]], [[6eii]], [[5oyf]], [[5ouu]], [[5oum]], [[5oul]], [[5oue]], [[5otz]], [[5oty]], [[5otr]], [[5otq]], [[5oto]], [[5otl]], [[5oti]], [[5oth]], [[5otd]], [[5ot6]], [[5ot5]], [[5osz]], [[5osl]], [[5os8]], [[5os7]], [[5ork]], [[5orj]], [[5orh]], [[5oqu]], [[5ooi]], [[5oni]], [[5n9k]], [[5mpj]], [[5mp8]], [[5mow]], [[5mov]], [[5mot]], [[5moh]], [[5moe]], [[5mod]], [[5mo8]], [[5mo7]], [[5mo6]], [[5mo5]], [[5mmr]], [[5mmf]] - hCK2 (mutant) + inhibitor<br /> |
**[[4fbx]] - hCK2 + polypeptide inhibitor<br /> | **[[4fbx]] - hCK2 + polypeptide inhibitor<br /> | ||
**[[4ib5]] - hCK2 + hCK2 β polypeptide <br /> | **[[4ib5]] - hCK2 + hCK2 β polypeptide <br /> | ||
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**[[4jqe]] - yCK2 + AMPPN<br /> | **[[4jqe]] - yCK2 + AMPPN<br /> | ||
**[[4jr7]], [[4lfi]] - yCK2 + GMPPNP<br /> | **[[4jr7]], [[4lfi]] - yCK2 + GMPPNP<br /> | ||
| + | **[[5xvu]] - CK2 + ATP – ''Plasmodium falciparum''<br /> | ||
*CK2 regulatory subunit | *CK2 regulatory subunit | ||
Revision as of 10:16, 5 April 2018
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3D Structures of casein kinase
Updated on 05-April-2018
References
- ↑ Eide EJ, Virshup DM. Casein kinase I: another cog in the circadian clockworks. Chronobiol Int. 2001 May;18(3):389-98. PMID:11475410
- ↑ Pinna LA, Meggio F. Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation. Prog Cell Cycle Res. 1997;3:77-97. PMID:9552408
- ↑ Hua Z, Huang X, Bregman H, Chakka N, DiMauro EF, Doherty EM, Goldstein J, Gunaydin H, Huang H, Mercede S, Newcomb J, Patel VF, Turci SM, Yan J, Wilson C, Martin MW. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1gamma) inhibitors. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. doi: 10.1016/j.bmcl.2012.07.046. , Epub 2012 Jul 20. PMID:22877629 doi:10.1016/j.bmcl.2012.07.046
