User:Evie Nguyen/Sandbox 1
From Proteopedia
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= HRP1 = | = HRP1 = | ||
| - | HRP1 is found in ''Saccharomyces cerevisiae'', commonly known as "baker's yeast." It was discovered via solution NMR and then released to the RCSB Protein Data Bank with the ID "2CJK" in 2006. HRP1 is the RNA recognition domain of the Cleavage Factor Complex, positioning the RNA cleavage site prior to polyadenylation. It is composed of 2 RNA binding domains that recognize a specific 5'-AUAUAU-3' sequence of RNA. | ||
| - | [[Image:2CJK.png|100 px|left|thumb|Figure Legend]]<Structure load='2CJK' size='350' frame='true' align='right' caption='2CJK' scene='Insert optional scene name here' /> | ||
| - | This is a default text for your page '''Evie Nguyen/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| - | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | <StructureSection load='2i2y' size='400' side='right' caption='SRp20 bound to RNA ligand and IgG binding domain 1 (PDB entry [[2i2y]])' scene=''> | ||
<scene name='78/782620/2cjk_residues_100-200-2/1'>2CJK Residues 100-200</scene> | <scene name='78/782620/2cjk_residues_100-200-2/1'>2CJK Residues 100-200</scene> | ||
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| + | ==Function== | ||
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=== Adenines === | === Adenines === | ||
| - | + | <StructureSection load='2i2y' size='400' side='right' caption='SRp20 bound to RNA ligand and IgG binding domain 1 (PDB entry [[2i2y]])' scene=''> | |
== Disease == | == Disease == | ||
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== Relevance == | == Relevance == | ||
Revision as of 18:06, 6 April 2018
Contents |
HRP1
Function
RNA Binding
The ribonucleotides of the recognized sequence 5'-AUAUAU-3' are designated from 5'-3' Ade2, Ade4, and Ade6; and Ura3, Ura5, and Ura7. The first two bases, Ade2 and Ura3, bind to the second RNA binding domain, and the remaining bases of the sequence bind to the first RNA binding domain. Each ribonucleotide has distinguishing interactions with the protein including
Adenines
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References
