6ch4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Aminoglycoside Phosphotransferase (2'')-Ia S376N mutant in complex with GMPPNP and Magnesium== | |
| - | + | <StructureSection load='6ch4' size='340' side='right' caption='[[6ch4]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ch4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CH4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ch4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ch4 OCA], [http://pdbe.org/6ch4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ch4 RCSB], [http://www.ebi.ac.uk/pdbsum/6ch4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ch4 ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Berghuis, A | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/AACA_STAAU AACA_STAAU]] Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Berghuis, A M]] | ||
| + | [[Category: Caldwell, S J]] | ||
| + | [[Category: Aminoglycoside]] | ||
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Resistance]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-antibiotic complex]] | ||
Revision as of 13:52, 11 April 2018
Aminoglycoside Phosphotransferase (2)-Ia S376N mutant in complex with GMPPNP and Magnesium
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