5v67
From Proteopedia
(Difference between revisions)
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<StructureSection load='5v67' size='340' side='right' caption='[[5v67]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='5v67' size='340' side='right' caption='[[5v67]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v67]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V67 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5v67]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V67 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IBI:N-{TRANS-4-[4-(CYCLOPROPYLMETHYL)PIPERAZIN-1-YL]CYCLOHEXYL}-4-{[(7R)-7-ETHYL-5-METHYL-8-(1-METHYLETHYL)-6-OXO-5,6,7,8-TETRAHYDROPTERIDIN-2-YL]AMINO}-3-METHOXYBENZAMIDE'>IBI</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IBI:N-{TRANS-4-[4-(CYCLOPROPYLMETHYL)PIPERAZIN-1-YL]CYCLOHEXYL}-4-{[(7R)-7-ETHYL-5-METHYL-8-(1-METHYLETHYL)-6-OXO-5,6,7,8-TETRAHYDROPTERIDIN-2-YL]AMINO}-3-METHOXYBENZAMIDE'>IBI</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v67 OCA], [http://pdbe.org/5v67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v67 RCSB], [http://www.ebi.ac.uk/pdbsum/5v67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v67 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v67 OCA], [http://pdbe.org/5v67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v67 RCSB], [http://www.ebi.ac.uk/pdbsum/5v67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v67 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
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| + | ==See Also== | ||
| + | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: EMBER, S W]] | [[Category: EMBER, S W]] | ||
[[Category: SCHONBRUNN, E]] | [[Category: SCHONBRUNN, E]] | ||
Revision as of 14:08, 11 April 2018
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH Volasertib
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