Complement C3

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**[[5fo9]] – hCC3 β+α’ chains + protein<br />
**[[5fo9]] – hCC3 β+α’ chains + protein<br />
**[[5foa]], [[5f08]], [[2icf]], [[2wii]] – hCC3 α+β chains + protein <br />
**[[5foa]], [[5f08]], [[2icf]], [[2wii]] – hCC3 α+β chains + protein <br />
-
**[[3g6j]] – hCC3 α+β chains + antibody<br />
+
**[[3g6j]], [[6ehg]] – hCC3 α+β chains + antibody<br />
 +
**[[5o35]] – hCC3 α chain + complement factor H<br />
 +
**[[5o32]] – hCC3 α chain + complement factor I<br />
**[[2xwb]] – hCC3 α+β chains + complement factor B + complement factor D<br />
**[[2xwb]] – hCC3 α+β chains + complement factor B + complement factor D<br />
**[[2xwj]] – hCC3 α+β chains (mutant) + complement factor B<br />
**[[2xwj]] – hCC3 α+β chains (mutant) + complement factor B<br />
 +
**[[5nbq]] – hCC3 α chain + complement factor B <br />
 +
**[[5fo8]] – hCC3 α chain + membrane cofactor protein<br />
 +
**[[5m6w]] – hCC3 α+β chains + complement factor H + complement inhibitor<br />
**[[3l5n]], [[3ohx]] – hCC3 α+β chains + protein inhibitor<br />
**[[3l5n]], [[3ohx]] – hCC3 α+β chains + protein inhibitor<br />
**[[2win]] – hCC3 α+β chains + complement factor B BB fragment + protein inhibitor<br />
**[[2win]] – hCC3 α+β chains + complement factor B BB fragment + protein inhibitor<br />

Revision as of 09:30, 12 April 2018

Structure of human glycosylated complement C3b α (magenta) and β (salmon) chains complex with protein CRIG (cyan) and Ca+2 ion (green) (PDB code 2icf).

Drag the structure with the mouse to rotate

3D structures of complement C3

Updated on 12-April-2018 

– hCC3 + inhibitor



References

  1. ↑ Sahu A, Lambris JD. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev. 2001 Apr;180:35-48. PMID:11414361
  2. ↑ Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:17051150 doi:10.1038/nature05263

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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