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Core-binding factor

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Line 32: Line 32:
*Core-binding factor β subunit
*Core-binding factor β subunit
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**[[1ilf]] – mCBFb<br />
+
**[[1ilf]], [[2jhb]] – mCBFb<br />
**[[4n9f]] – hCBFb + cullin-5 + transcription elongation factor B + virion infectivity factor<br />
**[[4n9f]] – hCBFb + cullin-5 + transcription elongation factor B + virion infectivity factor<br />

Revision as of 10:31, 15 April 2018

Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code 1h9d)

Drag the structure with the mouse to rotate

3D Structures of core-binding factor

Updated on 15-April-2018


References

  1. ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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