5vck

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'''Unreleased structure'''
 
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The entry 5vck is ON HOLD until Paper Publication
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==HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite==
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<StructureSection load='5vck' size='340' side='right' caption='[[5vck]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors: Tiefenbrunn, T., Stout, C.D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5vck]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VCK FirstGlance]. <br>
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Description: HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene>, <scene name='pdbligand=7GC:4-methyl-N-(thiazol-2-ylcarbamoyl)benzenesulfonamide'>7GC</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5to9|5to9]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vck OCA], [http://pdbe.org/5vck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vck RCSB], [http://www.ebi.ac.uk/pdbsum/5vck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vck ProSAT]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: HIV-1 retropepsin]]
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[[Category: Stout, C D]]
[[Category: Tiefenbrunn, T]]
[[Category: Tiefenbrunn, T]]
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[[Category: Stout, C.D]]
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[[Category: Allostery]]
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[[Category: Exosite]]
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[[Category: Fragment binding]]
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[[Category: Hydrolase]]
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[[Category: Protease]]

Revision as of 05:37, 18 April 2018

HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite

5vck, resolution 1.80Å

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