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1x86
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA== | ==Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA== | ||
<StructureSection load='1x86' size='340' side='right' caption='[[1x86]], [[Resolution|resolution]] 3.22Å' scene=''> | <StructureSection load='1x86' size='340' side='right' caption='[[1x86]], [[Resolution|resolution]] 3.22Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1txd|1txd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1txd|1txd]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF12, LARG, KIAA0382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RHOA, ARHA, ARH12, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF12, LARG, KIAA0382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RHOA, ARHA, ARH12, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x86 OCA], [http://pdbe.org/1x86 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x86 RCSB], [http://www.ebi.ac.uk/pdbsum/1x86 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x86 OCA], [http://pdbe.org/1x86 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x86 RCSB], [http://www.ebi.ac.uk/pdbsum/1x86 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x86 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x86_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x86_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x86 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
| + | *[[Rho GTPase|Rho GTPase]] | ||
*[[Rho guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor]] | *[[Rho guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor]] | ||
== References == | == References == | ||
Revision as of 06:57, 18 April 2018
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
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