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== Disease ==
== Disease ==
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IL-6 has been found to be involved with the maintenance of bone homeostasis, as an increase in IL-6 levels has strongly reported in illnesses such as Paget’s disease and myeloma, where significant bone loss occurs.
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IL-6 has been found to be involved with the maintenance of bone homeostasis, as an increase in IL-6 levels has strongly reported in illnesses such as Paget’s disease and myeloma, where significant bone loss occurs. IL-6 has also been implicated in Castleman Disease.
== Relevance ==
== Relevance ==
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IL-6 is produced is produced by wide range of cells that include not just cells of the immune system. Its production is induced by immune response, but can be affected by various antigenic factors.
== Structural highlights ==
== Structural highlights ==

Revision as of 22:57, 22 April 2018

Structure: Human Interleukin-6

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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