2hcy
From Proteopedia
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|PDB= 2hcy |SIZE=350|CAPTION= <scene name='initialview01'>2hcy</scene>, resolution 2.44Å | |PDB= 2hcy |SIZE=350|CAPTION= <scene name='initialview01'>2hcy</scene>, resolution 2.44Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=8ID:NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE'>8ID</scene>, <scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span> |
|GENE= ADH1, ADC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]) | |GENE= ADH1, ADC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hcy OCA], [http://www.ebi.ac.uk/pdbsum/2hcy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hcy RCSB]</span> | ||
}} | }} | ||
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[[Category: Ramaswamy, S.]] | [[Category: Ramaswamy, S.]] | ||
[[Category: Savarimuthu, B R.]] | [[Category: Savarimuthu, B R.]] | ||
| - | [[Category: 8ID]] | ||
| - | [[Category: ETF]] | ||
| - | [[Category: ZN]] | ||
[[Category: intramolecular disulfide bond]] | [[Category: intramolecular disulfide bond]] | ||
[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
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[[Category: zinc coordination]] | [[Category: zinc coordination]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:28:37 2008'' |
Revision as of 00:28, 31 March 2008
| |||||||
| , resolution 2.44Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | ADH1, ADC1 (Saccharomyces cerevisiae) | ||||||
| Activity: | Alcohol dehydrogenase, with EC number 1.1.1.1 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Yeast Alcohol Dehydrogenase I, Saccharomyces cerevisiae fermentative enzyme
Overview
The cytoplasmic yeast alcohol dehydrogenase I crystallized at 5 degrees C as hexagonal plates or short columns in the presence of NAD+ and 2,2,2-trifluoroethanol, in sodium N-tris(hydroxymethyl)methyl-3-aminopropanesulfonate buffer at pH 8.2 to 8.6, using polyethylene glycol 4000 as precipitant. X-ray diffraction data to 3.2 A resolution show that the crystals are hexagonal in space group P622 with unit cell dimensions a = b = 147.9 A, c = 69.1 A. There is one subunit of the tetrameric enzyme per asymmetric unit, giving a packing density of 2.9 A3/Da.
About this Structure
2HCY is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
Crystallization and preliminary crystallographic studies of Saccharomyces cerevisiae alcohol dehydrogenase I., Ramaswamy S, Kratzer DA, Hershey AD, Rogers PH, Arnone A, Eklund H, Plapp BV, J Mol Biol. 1994 Jan 14;235(2):777-9. PMID:8289298
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