5zbq
From Proteopedia
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- | '''Unreleased structure''' | ||
- | The | + | ==The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299== |
- | + | <StructureSection load='5zbq' size='340' side='right' caption='[[5zbq]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5zbq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZBQ FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9AO:N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide'>9AO</scene></td></tr> | |
- | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zbh|5zbh]]</td></tr> |
+ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zbq OCA], [http://pdbe.org/5zbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zbq RCSB], [http://www.ebi.ac.uk/pdbsum/5zbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zbq ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/NPY1R_HUMAN NPY1R_HUMAN]] Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Lysozyme]] | ||
+ | [[Category: Han, S]] | ||
[[Category: Wu, B]] | [[Category: Wu, B]] | ||
[[Category: Yang, Z]] | [[Category: Yang, Z]] | ||
- | [[Category: Han, S]] | ||
[[Category: Zhao, Q]] | [[Category: Zhao, Q]] | ||
+ | [[Category: Complex structure]] | ||
+ | [[Category: G protein-coupled receptor]] | ||
+ | [[Category: Receptor inhibitor]] | ||
+ | [[Category: Signaling protein]] |
Revision as of 05:31, 25 April 2018
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
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