6gak
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the T1L reovirus sigma1 coiled coil tail (chloride)== | |
| - | + | <StructureSection load='6gak' size='340' side='right' caption='[[6gak]], [[Resolution|resolution]] 1.43Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gak]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GAK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gak OCA], [http://pdbe.org/6gak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gak RCSB], [http://www.ebi.ac.uk/pdbsum/6gak PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gak ProSAT]</span></td></tr> |
| - | [[Category: Dietrich, M | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SIGM1_REOVL SIGM1_REOVL]] Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dietrich, M H]] | ||
[[Category: Stehle, T]] | [[Category: Stehle, T]] | ||
| + | [[Category: Cell attachment protein]] | ||
| + | [[Category: Coiled coil]] | ||
| + | [[Category: Reovirus sigma1]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 05:39, 25 April 2018
Crystal structure of the T1L reovirus sigma1 coiled coil tail (chloride)
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