Garman lab: Interconversion of lysosomal enzyme specificities
From Proteopedia
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Panel B <scene name='78/786673/Gal_overall/1'>overall structure</scene> (<scene name='78/786673/Gal_active_site/1'>show detail</scene>) | Panel B <scene name='78/786673/Gal_overall/1'>overall structure</scene> (<scene name='78/786673/Gal_active_site/1'>show detail</scene>) | ||
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| - | Crystalline structure of alpha-GAL(SA) bound to GalNAc. Residues, in yellow, represent active sites for alpha-GAL(SA) and residues, in gray, represent GalNAc. The blue frame around GalNAc represents its electron density. Red and blue dots in the figure represent oxygen and hydrogen, respectively. | ||
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Panel C <scene name='78/786673/Nagal_overall/2'>overall structure</scene> (show <scene name='78/786673/Nagal_active_site/2'>detail</scene>) | Panel C <scene name='78/786673/Nagal_overall/2'>overall structure</scene> (show <scene name='78/786673/Nagal_active_site/2'>detail</scene>) | ||
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<scene name='78/786673/Fig2a_galnac_complex/1'>Panel A</scene>: in complex with GalNAc | <scene name='78/786673/Fig2a_galnac_complex/1'>Panel A</scene>: in complex with GalNAc | ||
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| + | Crystalline structure of alpha-GAL(SA) bound to GalNAc. Residues, in yellow, represent active sites for alpha-GAL(SA) and residues, in gray, represent GalNAc. The blue frame around GalNAc represents its electron density. Red and blue dots in the figure represent oxygen and hydrogen, respectively. | ||
<scene name='78/786673/Galsa_nagal/1'>Panel D</scene>: Superposition with alpha-NAGAL bound to GalNAc | <scene name='78/786673/Galsa_nagal/1'>Panel D</scene>: Superposition with alpha-NAGAL bound to GalNAc | ||
</StructureSection> | </StructureSection> | ||
Revision as of 17:25, 1 May 2018
Contents |
About this page
Lysosomal storage disease
Antigenicity
Enzymatic activity
the earth is flat
Structures shown on this page
3H54: alpha-NAGAL with GalNAc
3HG5: alpha-GAL with Gal
3LX9: alpha-GAL(SA) in complex with GalNAc
3LXA: alpha-GAL(SA) in complex with Galactose
3LXC: alpha-GAL(SA) in presence of Glycerol
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