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6b0i
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Apo KLP10A in complex with a microtubule== | |
| - | + | <StructureSection load='6b0i' size='340' side='right' caption='[[6b0i]], [[Resolution|resolution]] 3.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6b0i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B0I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0i OCA], [http://pdbe.org/6b0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b0i RCSB], [http://www.ebi.ac.uk/pdbsum/6b0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0i ProSAT]</span></td></tr> |
| - | [[Category: Benoit, M | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/F2Z5B2_PIG F2Z5B2_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU003505] [[http://www.uniprot.org/uniprot/KI10A_DROME KI10A_DROME]] Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux".<ref>PMID:14681690</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Asenjo, A B]] | ||
| + | [[Category: Benoit, M P.M H]] | ||
[[Category: Sosa, H]] | [[Category: Sosa, H]] | ||
| - | [[Category: | + | [[Category: Depolymerization]] |
| + | [[Category: Kinesin 13]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Motor protein-structural protein complex]] | ||
| + | [[Category: Tubulin]] | ||
Revision as of 08:07, 2 May 2018
Apo KLP10A in complex with a microtubule
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