6d0a
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution== | |
| - | + | <StructureSection load='6d0a' size='340' side='right' caption='[[6d0a]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d0a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D0A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d0a OCA], [http://pdbe.org/6d0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d0a RCSB], [http://www.ebi.ac.uk/pdbsum/6d0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d0a ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/AADAT_HUMAN AADAT_HUMAN]] Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).<ref>PMID:18620547</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Church, W B]] | ||
| + | [[Category: Jayawickrama, G S]] | ||
[[Category: Nematollahi, A]] | [[Category: Nematollahi, A]] | ||
| - | [[Category: Jayawickrama, G.S]] | ||
[[Category: Sun, G]] | [[Category: Sun, G]] | ||
| + | [[Category: Alpha-beta fold]] | ||
| + | [[Category: Hexahistidine tag]] | ||
| + | [[Category: Plp-dependent]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:12, 2 May 2018
Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution
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