This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6d0a
From Proteopedia
(Difference between revisions)
m (Protected "6d0a" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution== | |
| - | + | <StructureSection load='6d0a' size='340' side='right' caption='[[6d0a]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d0a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D0A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d0a OCA], [http://pdbe.org/6d0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d0a RCSB], [http://www.ebi.ac.uk/pdbsum/6d0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d0a ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/AADAT_HUMAN AADAT_HUMAN]] Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).<ref>PMID:18620547</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Church, W B]] | ||
| + | [[Category: Jayawickrama, G S]] | ||
[[Category: Nematollahi, A]] | [[Category: Nematollahi, A]] | ||
| - | [[Category: Jayawickrama, G.S]] | ||
[[Category: Sun, G]] | [[Category: Sun, G]] | ||
| + | [[Category: Alpha-beta fold]] | ||
| + | [[Category: Hexahistidine tag]] | ||
| + | [[Category: Plp-dependent]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:12, 2 May 2018
Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution
| |||||||||||
