6d47
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum== | |
| - | + | <StructureSection load='6d47' size='340' side='right' caption='[[6d47]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d47]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D47 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d47 OCA], [http://pdbe.org/6d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d47 RCSB], [http://www.ebi.ac.uk/pdbsum/6d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d47 ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Griselimycin]] | ||
| + | [[Category: Mtb]] | ||
| + | [[Category: National institute of allergy and infectious disease]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Ssgcid]] | ||
| + | [[Category: Tuberculosis]] | ||
Revision as of 08:12, 2 May 2018
Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum
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