Anthrax edema factor
From Proteopedia
(Difference between revisions)
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*<scene name='48/485623/Cv/2'>EF trimer with 3 calmodulin molecules</scene>. | *<scene name='48/485623/Cv/2'>EF trimer with 3 calmodulin molecules</scene>. | ||
| - | *<scene name='48/485623/Cv/ | + | *<scene name='48/485623/Cv/5'>ADP derivative/Yt+3 binding site</scene> of EF. Water molecules are shown as red spheres. |
| - | *<scene name='48/485623/Cv/ | + | *<scene name='48/485623/Cv/6'>Ca+2 binding site</scene> of calmodulin (PDB code [[1pk0]]).<ref>PMID:14978283</ref> |
</StructureSection> | </StructureSection> | ||
Revision as of 13:47, 7 May 2018
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3D structures of anthrax edema factor
Updated on 07-May-2018
1lvc – EF adenylate cyclase domain C terminal + calmodulin + anthraniloyl-deoxy-ATP
1pk0 - EF adenylate cyclase domain C terminal + calmodulin + phosphonylmethoxyethyl-ADP
1s26 - EF adenylate cyclase domain C terminal + calmodulin + methylene-ATP
1sk6 - EF adenylate cyclase domain C terminal + calmodulin + pyrophosphate + cAMP
1xfu - EF (mutant) + calmodulin
1xfv - EF + calmodulin + deoxy-ATP
1xfw - EF + calmodulin + cAMP
1xfx, 1xfy, 1xfz - EF + calmodulin
References
- ↑ Abrami L, Reig N, van der Goot FG. Anthrax toxin: the long and winding road that leads to the kill. Trends Microbiol. 2005 Feb;13(2):72-8. PMID:15680766 doi:http://dx.doi.org/10.1016/j.tim.2004.12.004
- ↑ Shen Y, Zhukovskaya NL, Zimmer MI, Soelaiman S, Bergson P, Wang CR, Gibbs CS, Tang WJ. Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3242-7. Epub 2004 Feb 20. PMID:14978283 doi:10.1073/pnas.0306552101
