5o6j
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-1031== | |
| - | + | <StructureSection load='5o6j' size='340' side='right' caption='[[5o6j]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5o6j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O6J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9M8:1-[5-[3-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine'>9M8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5o6h|5o6h]], [[5mu6|5mu6]]</td></tr> |
| - | [[Category: Wilkinson, A | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o6j OCA], [http://pdbe.org/5o6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o6j RCSB], [http://www.ebi.ac.uk/pdbsum/5o6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o6j ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glycylpeptide N-tetradecanoyltransferase]] | ||
| + | [[Category: Brannigan, J A]] | ||
| + | [[Category: Wilkinson, A J]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Myristoyl]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:23, 16 May 2018
Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-1031
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