6bbd

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'''Unreleased structure'''
 
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The entry 6bbd is ON HOLD until Paper Publication
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==Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol==
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<StructureSection load='6bbd' size='340' side='right' caption='[[6bbd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: van Eijk, M., Rynkiewicz, M.J., Khatri, K., Leymarie, N., Zaia, J., White, M.R., Hartshorn, K.L., Cafarella, T.R., van Die, I., Hessing, M., Seaton, B.A., Haagsman, H.P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BBD FirstGlance]. <br>
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Description: Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dn8|4dn8]]</td></tr>
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[[Category: White, M.R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bbd OCA], [http://pdbe.org/6bbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bbd RCSB], [http://www.ebi.ac.uk/pdbsum/6bbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bbd ProSAT]</span></td></tr>
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[[Category: Seaton, B.A]]
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</table>
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[[Category: Haagsman, H.P]]
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== Function ==
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[[Category: Cafarella, T.R]]
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[[http://www.uniprot.org/uniprot/SFTPD_PIG SFTPD_PIG]] Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity).
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[[Category: Hartshorn, K.L]]
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__TOC__
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</StructureSection>
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[[Category: Cafarella, T R]]
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[[Category: Die, I van]]
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[[Category: Eijk, M van]]
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[[Category: Haagsman, H P]]
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[[Category: Hartshorn, K L]]
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[[Category: Hessing, M]]
[[Category: Khatri, K]]
[[Category: Khatri, K]]
[[Category: Leymarie, N]]
[[Category: Leymarie, N]]
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[[Category: Van Eijk, M]]
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[[Category: Rynkiewicz, M J]]
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[[Category: Hessing, M]]
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[[Category: Seaton, B A]]
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[[Category: Van Die, I]]
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[[Category: White, M R]]
[[Category: Zaia, J]]
[[Category: Zaia, J]]
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[[Category: Rynkiewicz, M.J]]
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[[Category: C-type lectin]]
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[[Category: Innate immunity]]
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[[Category: N-linked glycan]]
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[[Category: Surfactant]]
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[[Category: Surfactant protein]]

Revision as of 07:19, 23 May 2018

Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol

6bbd, resolution 1.90Å

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