6gdi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state== | |
| - | + | <StructureSection load='6gdi' size='340' side='right' caption='[[6gdi]], [[Resolution|resolution]] 7.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gdi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GDI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gdi OCA], [http://pdbe.org/6gdi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gdi RCSB], [http://www.ebi.ac.uk/pdbsum/6gdi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gdi ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Xenobiotic-transporting ATPase]] | ||
[[Category: Barbieri, A]] | [[Category: Barbieri, A]] | ||
| + | [[Category: Collins, R F]] | ||
| + | [[Category: Ford, R C]] | ||
[[Category: Shafi, T]] | [[Category: Shafi, T]] | ||
| + | [[Category: Siebert, A]] | ||
| + | [[Category: Thonghin, N]] | ||
| + | [[Category: Abcb1]] | ||
| + | [[Category: Atp-binding cassette]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: P-glycoprotein]] | ||
| + | [[Category: Protein structure]] | ||
| + | [[Category: Transporter]] | ||
Revision as of 07:30, 23 May 2018
Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state
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