Flagellin

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Line 26: Line 26:
**[[5tfy]] – Fla – ''Methanospirillum hungatei'' – Cryo EM <br />
**[[5tfy]] – Fla – ''Methanospirillum hungatei'' – Cryo EM <br />
**[[5wjt]], [[5wju]], [[5wjv]], [[5wjw]], [[5wjx]], [[5wjy]], [[5wjz]] – BsFla – ''Bacillus subtilis'' – Cryo EM<br />
**[[5wjt]], [[5wju]], [[5wjv]], [[5wjw]], [[5wjx]], [[5wjy]], [[5wjz]] – BsFla – ''Bacillus subtilis'' – Cryo EM<br />
 +
**[[2zbi]] – Fla - ''Sphingomonas''<br />
* Flagellin complex
* Flagellin complex
Line 34: Line 35:
**[[5gy2]] – BsFla residues 54-230 + TLR5 <br />
**[[5gy2]] – BsFla residues 54-230 + TLR5 <br />
**[[1ory]] – AaFla FliC residues 464-518 + FliS <br />
**[[1ory]] – AaFla FliC residues 464-518 + FliS <br />
-
 
+
**[[5yud]] – StFla + Naip5 <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:03, 27 May 2018

Glycosylated flagellin (pink, yellow) complex with TLR5 (grey, green) (PDB code 3v47)

Drag the structure with the mouse to rotate

3D Structures of flagellin

Updated on 27-May-2018

References

  1. Zeng H, Carlson AQ, Guo Y, Yu Y, Collier-Hyams LS, Madara JL, Gewirtz AT, Neish AS. Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella. J Immunol. 2003 Oct 1;171(7):3668-74. PMID:14500664
  2. Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001 Apr 26;410(6832):1099-103. PMID:11323673 doi:http://dx.doi.org/10.1038/35074106
  3. Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA. Structural basis of TLR5-flagellin recognition and signaling. Science. 2012 Feb 17;335(6070):859-64. PMID:22344444 doi:10.1126/science.1215584

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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