This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6fjm
From Proteopedia
(Difference between revisions)
m (Protected "6fjm" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==tubulin-Disorazole Z complex== | |
| - | + | <StructureSection load='6fjm' size='340' side='right' caption='[[6fjm]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fjm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FJM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DKN:Disorazole+Z'>DKN</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fii|6fii]], [[6fjf|6fjf]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fjm OCA], [http://pdbe.org/6fjm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fjm RCSB], [http://www.ebi.ac.uk/pdbsum/6fjm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fjm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Agell, D Lucena]] | ||
| + | [[Category: Altmann, K H]] | ||
| + | [[Category: Bucher, P]] | ||
| + | [[Category: Diaz, J F]] | ||
| + | [[Category: Irschik, H]] | ||
| + | [[Category: Jansen, R]] | ||
| + | [[Category: Menchon, G]] | ||
| + | [[Category: Mueller, R]] | ||
| + | [[Category: Paterson, I]] | ||
| + | [[Category: Prota, A E]] | ||
| + | [[Category: Steinmetz, M O]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Cytoskeleton]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Tubulin fold]] | ||
Revision as of 05:39, 30 May 2018
tubulin-Disorazole Z complex
| |||||||||||
Categories: Bos taurus | Agell, D Lucena | Altmann, K H | Bucher, P | Diaz, J F | Irschik, H | Jansen, R | Menchon, G | Mueller, R | Paterson, I | Prota, A E | Steinmetz, M O | Cell cycle | Cytoskeleton | Microtubule | Tubulin fold
