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2iub
From Proteopedia
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|PDB= 2iub |SIZE=350|CAPTION= <scene name='initialview01'>2iub</scene>, resolution 2.90Å | |PDB= 2iub |SIZE=350|CAPTION= <scene name='initialview01'>2iub</scene>, resolution 2.90Å | ||
|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+G'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+G'>AC1</scene> | ||
| - | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> | + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2bbh|2BBH]], [[2bbj|2BBJ]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iub OCA], [http://www.ebi.ac.uk/pdbsum/2iub PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iub RCSB]</span> | ||
}} | }} | ||
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[[Category: Niegowski, D.]] | [[Category: Niegowski, D.]] | ||
[[Category: Nordlund, P.]] | [[Category: Nordlund, P.]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: MG]] | ||
[[Category: cora]] | [[Category: cora]] | ||
[[Category: divalent cation]] | [[Category: divalent cation]] | ||
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[[Category: membrane protein]] | [[Category: membrane protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:48:45 2008'' |
Revision as of 00:48, 31 March 2008
| |||||||
| , resolution 2.90Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , | ||||||
| Related: | 2BBH, 2BBJ
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.
Overview
CorA family members are ubiquitously distributed transporters of divalent metal cations and are considered to be the primary Mg2+ transporter of Bacteria and Archaea. We have determined a 2.9 angstrom resolution structure of CorA from Thermotoga maritima that reveals a pentameric cone-shaped protein. Two potential regulatory metal binding sites are found in the N-terminal domain that bind both Mg2+ and Co2+. The structure of CorA supports an efflux system involving dehydration and rehydration of divalent metal ions potentially mediated by a ring of conserved aspartate residues at the cytoplasmic entrance and a carbonyl funnel at the periplasmic side of the pore.
About this Structure
2IUB is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.
Reference
Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution., Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P, Science. 2006 Jul 21;313(5785):354-7. PMID:16857941
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