Sandbox 7712
From Proteopedia
(Difference between revisions)
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- | 1ACJ* shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine | + | 1ACJ* shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine |
Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease. | Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease. |
Revision as of 22:01, 4 June 2018
Your Heading Here (maybe something like 'Structure')
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References
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649