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| - | | + | #REDIRECT [[6d0s]] This PDB entry is obsolete and replaced by 6d0s |
| - | ==Crystal structure of the RabGAP domain of human TBC1D22B==
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| - | <StructureSection load='3dzx' size='340' side='right' caption='[[3dzx]], [[Resolution|resolution]] 2.30Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3dzx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DZX FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TBC1D22B, C6orf197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dzx OCA], [http://pdbe.org/3dzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dzx RCSB], [http://www.ebi.ac.uk/pdbsum/3dzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dzx ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/TB22B_HUMAN TB22B_HUMAN]] May act as a GTPase-activating protein for Rab family protein(s).
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| - | == Evolutionary Conservation ==
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| - | [[Image:Consurf_key_small.gif|200px|right]]
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| - | Check<jmol>
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| - | <jmolCheckbox>
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| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/3dzx_consurf.spt"</scriptWhenChecked>
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| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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| - | <text>to colour the structure by Evolutionary Conservation</text>
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| - | </jmolCheckbox>
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| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dzx ConSurf].
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| - | <div style="clear:both"></div>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Human]]
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| - | [[Category: Arrowsmith, C H]]
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| - | [[Category: Bochkarev, A]]
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| - | [[Category: Bountra, C]]
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| - | [[Category: Edwards, A M]]
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| - | [[Category: Mackenzie, F]]
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| - | [[Category: Nedyalkova, L]]
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| - | [[Category: Park, H]]
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| - | [[Category: Structural genomic]]
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| - | [[Category: Shen, Y]]
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| - | [[Category: Tempel, W]]
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| - | [[Category: Tong, Y]]
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| - | [[Category: Wilkstrom, M]]
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| - | [[Category: Gtpase activation]]
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| - | [[Category: Gtpase activator]]
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| - | [[Category: Hydrolase activator]]
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| - | [[Category: Rab-gap]]
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| - | [[Category: Sgc]]
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| - | [[Category: Signaling protein]]
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| - | [[Category: Tbc1]]
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