This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2j0f
From Proteopedia
| Line 5: | Line 5: | ||
|SITE= <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene> | ||
|LIGAND= <scene name='pdbligand=TDR:THYMINE'>TDR</scene> | |LIGAND= <scene name='pdbligand=TDR:THYMINE'>TDR</scene> | ||
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j0f OCA], [http://www.ebi.ac.uk/pdbsum/2j0f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2j0f RCSB]</span> | ||
}} | }} | ||
'''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN''' | '''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Mitochondrial neurogastrointestinal encephalomyopathy syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131222 131222]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 26: | Line 26: | ||
[[Category: Perez-Perez, M J.]] | [[Category: Perez-Perez, M J.]] | ||
[[Category: Stammers, D K.]] | [[Category: Stammers, D K.]] | ||
| - | [[Category: TDR]] | ||
[[Category: angiogenesis]] | [[Category: angiogenesis]] | ||
[[Category: chemotaxis]] | [[Category: chemotaxis]] | ||
| Line 39: | Line 38: | ||
[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:51:18 2008'' |
Revision as of 00:51, 31 March 2008
| |||||||
| , resolution 2.31Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | |||||||
| Activity: | Thymidine phosphorylase, with EC number 2.4.2.4 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN
About this Structure
2J0F is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 03:51:18 2008
Categories: Homo sapiens | Single protein | Thymidine phosphorylase | Balzarini, J. | Bronckaers, A. | Liekens, S. | Omari, K El. | Perez-Perez, M J. | Stammers, D K. | Angiogenesis | Chemotaxis | Developmental protein | Differentiation | Disease mutation | Glycosyltransferase | Growth factor | Htp | Human thymidine phosphorylase | Polymorphism | Transferase
