Gp41

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*Gp41 from HIV-1
*Gp41 from HIV-1
-
**[[1aik]] – Gp41 <br />
+
**[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 thermostable core domain residues 544-579, 623-656<br />
-
**[[1env]], [[3k9a]] – Gp41 (mutant)<br />
+
**[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]] – Gp41 thermostable core domain (mutant)<br />
-
**[[1szt]] – Gp41 thermostable domain<br />
+
**[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
-
**[[3cp1]], [[3cyo]] – Gp41 thermostable domain (mutant)<br />
+
**[[1szt]] – Gp41 thermostable domain residues 541-574<br />
-
**[[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 core<br />
+
**[[6b3u]] – Gp41 transmembrane domain residues 670-709 - NMR<br />
-
**[[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]] – Gp41 core (mutant)<br />
+
**[[5vwl]] – Gp41 tail residues 750-854 - NMR<br />
-
**[[5ka6]], [[5ka5]] – Gp41 transmembrane (mutant)<br />
+
**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]], [[5h0n]] – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]], [[5h0n]] – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
-
**[[2zfc]] – Gp41 N-peptide <br />
+
**[[2zfc]] – Gp41 N-terminal residues 1-49 <br />
-
**[[4i2l]] – Gp41 N-peptide (mutant)<br />
+
**[[3u91]] – Gp41 N-terminal residues 7-39<br />
-
**[[3u91]] – Gp41 N-terminal <br />
+
**[[4hlr]] – Gp41 N-terminal (mutant) <br />
**[[4hlr]] – Gp41 N-terminal (mutant) <br />
-
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]] – Gp41 + Gp120 + antibody<br />
+
**[[4i2l]] – Gp41 N-peptide residues 549-589 (mutant)<br />
 +
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]] – Gp41 + Gp120 + antibody<br />
 +
**[[6cdi]] – Gp41 + Gp120 + antibody – Cryo EM<br />
**[[5u1f]], [[5thr]] – Gp41 + Gp120 + antibody + CD4<br />
**[[5u1f]], [[5thr]] – Gp41 + Gp120 + antibody + CD4<br />
**[[5fyk]], [[5fyj]], [[4nco]] – Gp41 + Gp120 (mutant) + antibody<br />
**[[5fyk]], [[5fyj]], [[4nco]] – Gp41 + Gp120 (mutant) + antibody<br />

Revision as of 08:10, 6 June 2018

Core structure of acetylated gp41 from the HIV envelope glycoprotein, 1aik.

Drag the structure with the mouse to rotate

3D Structures of Gp41

Updated on 06-June-2018

References

  1. ↑ Chan DC, Kim PS. HIV entry and its inhibition. Cell. 1998 May 29;93(5):681-4. PMID:9630213
  2. ↑ Root MJ, Steger HK. HIV-1 gp41 as a target for viral entry inhibition. Curr Pharm Des. 2004;10(15):1805-25. PMID:15180542

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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