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5w3g
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution Structure of ETS Transcription Factor PU.1== | |
| - | + | <StructureSection load='5w3g' size='340' side='right' caption='[[5w3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5w3g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W3G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3g OCA], [http://pdbe.org/5w3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w3g RCSB], [http://www.ebi.ac.uk/pdbsum/5w3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3g ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: Lau, D | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Note=Involved in murine acute Friend erythroleukemia. It is a target region for SFFV proviral insertion. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.<ref>PMID:8626664</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lau, D K.W]] | ||
| + | [[Category: McIntosh, L P]] | ||
[[Category: Okon, M]] | [[Category: Okon, M]] | ||
| - | [[Category: | + | [[Category: Dna binding protein]] |
| + | [[Category: Winged helix-turn-helix]] | ||
Revision as of 07:32, 14 June 2018
Solution Structure of ETS Transcription Factor PU.1
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