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6gmb
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate== | |
| - | + | <StructureSection load='6gmb' size='340' side='right' caption='[[6gmb]], [[Resolution|resolution]] 1.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOA:GLYCOLIC+ACID'>GOA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nzl|2nzl]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmb OCA], [http://pdbe.org/6gmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmb RCSB], [http://www.ebi.ac.uk/pdbsum/6gmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmb ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bezerra, G A]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Brennan, P E]] | ||
| + | [[Category: Edwards, E]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| - | [[Category: | + | [[Category: MacKinnon, S]] |
| - | + | ||
[[Category: Oppermann, U]] | [[Category: Oppermann, U]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Smee, C]] |
| - | [[Category: | + | [[Category: Yue, W W]] |
| - | [[Category: | + | [[Category: Fmn]] |
| + | [[Category: Glycolate]] | ||
| + | [[Category: Glyoxylate]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Peroxisome]] | ||
| + | [[Category: Primary hyperoxaluria]] | ||
| + | [[Category: Sgc]] | ||
Revision as of 07:46, 14 June 2018
Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
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Categories: Arrowsmith, C H | Bezerra, G A | Bountra, C | Brennan, P E | Edwards, E | Krojer, T | MacKinnon, S | Oppermann, U | Structural genomic | Smee, C | Yue, W W | Fmn | Glycolate | Glyoxylate | Oxidoreductase | Peroxisome | Primary hyperoxaluria | Sgc
