High mobility group protein

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Line 25: Line 25:
**[[2ezd]], [[2eze]], [[2ezf]], [[2ezg]] – hHMG-1 + DNA - human<br />
**[[2ezd]], [[2eze]], [[2ezf]], [[2ezg]] – hHMG-1 + DNA - human<br />
-
*HMGB
+
*HMGB box 1 domain residues 1-84; tandem boxes domain residues 1-166
**[[1hme]], [[1hmf]] – rHMG-1 B domain – rat - NMR <br />
**[[1hme]], [[1hmf]] – rHMG-1 B domain – rat - NMR <br />
Line 34: Line 34:
**[[2rtu]] – hHMG-1 box 1 - NMR<br />
**[[2rtu]] – hHMG-1 box 1 - NMR<br />
**[[2ly4]] – hHMG-1 box domain + cellular tumor antigen p53 - NMR<br />
**[[2ly4]] – hHMG-1 box domain + cellular tumor antigen p53 - NMR<br />
 +
**[[6cij]], [[6cik]], [[6cil]], [[6cim]] – hHMG-1 tandem boxes + RAG-1 + RAG-2 + DNA<br />
 +
**[[6cg0]] – hHMG-1 tandem boxes + RAG-1 + RAG-2 + DNA – Cryo EM<br />
 +
**[[5ze2]], [[5ze1]], [[5ze0]], [[5zdz]] – HMG-1 tandem boxes + RAG-1 + RAG-2 + DNA – mouse<br />
**[[2eqz]], [[2yqi]] – hHMG-3 box domain - NMR<br />
**[[2eqz]], [[2yqi]] – hHMG-3 box domain - NMR<br />
**[[1hsm]], [[1hsn]], [[1nhm]], [[1nhn]] – HMG-1 box domain – chinese hamster - NMR <br />
**[[1hsm]], [[1hsn]], [[1nhm]], [[1nhn]] – HMG-1 box domain – chinese hamster - NMR <br />

Revision as of 10:20, 18 June 2018

Rat HMGB1 tandem boxes complexed with DNA (PDB code 2gzk).

Drag the structure with the mouse to rotate

3D Structures of high mobility group protein (HMG)

Updated on 18-June-2018

References

  1. Bianchi ME, Manfredi AA. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev. 2007 Dec;220:35-46. PMID:17979838 doi:http://dx.doi.org/10.1111/j.1600-065X.2007.00574.x
  2. Fedele M, Battista S, Manfioletti G, Croce CM, Giancotti V, Fusco A. Role of the high mobility group A proteins in human lipomas. Carcinogenesis. 2001 Oct;22(10):1583-91. PMID:11576996
  3. Tang D, Kang R, Zeh HJ 3rd, Lotze MT. High-mobility group box 1 and cancer. Biochim Biophys Acta. 2010 Jan-Feb;1799(1-2):131-40. doi:, 10.1016/j.bbagrm.2009.11.014. PMID:20123075 doi:http://dx.doi.org/10.1016/j.bbagrm.2009.11.014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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