This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jf9
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2jf9 |SIZE=350|CAPTION= <scene name='initialview01'>2jf9</scene>, resolution 2.10Å | |PDB= 2jf9 |SIZE=350|CAPTION= <scene name='initialview01'>2jf9</scene>, resolution 2.10Å | ||
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+R'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+R'>AC1</scene> | ||
| - | |LIGAND= <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jf9 OCA], [http://www.ebi.ac.uk/pdbsum/2jf9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jf9 RCSB]</span> | ||
}} | }} | ||
'''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST''' | '''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Estrogen resistance OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], HDL response to hormone replacement, augmented OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Migraine, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 25: | Line 25: | ||
[[Category: Pike, A C.W.]] | [[Category: Pike, A C.W.]] | ||
[[Category: Treuter, E.]] | [[Category: Treuter, E.]] | ||
| - | [[Category: BCT]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: EDO]] | ||
| - | [[Category: OHT]] | ||
[[Category: alternative splicing]] | [[Category: alternative splicing]] | ||
[[Category: dna-binding]] | [[Category: dna-binding]] | ||
| Line 47: | Line 43: | ||
[[Category: zinc-finger]] | [[Category: zinc-finger]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:57:21 2008'' |
Revision as of 00:57, 31 March 2008
| |||||||
| , resolution 2.10Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST
About this Structure
2JF9 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 03:57:21 2008
Categories: Homo sapiens | Single protein | Gustafsson, J A. | Heldring, N. | Mcdonnell, D. | Pawson, T. | Pike, A C.W. | Treuter, E. | Alternative splicing | Dna-binding | Ligand-binding domain (lbd) | Lipid-binding | Metal-binding | Nuclear protein | Nuclear receptor | Peptide antagonist | Phosphorylation | Polymorphism | Receptor | Steroid-binding | Transcription | Transcription factor | Transcription regulation | Zinc | Zinc-finger
