This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jh0
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2jh0 |SIZE=350|CAPTION= <scene name='initialview01'>2jh0</scene>, resolution 1.70Å | |PDB= 2jh0 |SIZE=350|CAPTION= <scene name='initialview01'>2jh0</scene>, resolution 1.70Å | ||
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+D'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+D'>AC1</scene> | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=701:(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE'>701</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jh0 OCA], [http://www.ebi.ac.uk/pdbsum/2jh0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jh0 RCSB]</span> | ||
}} | }} | ||
'''HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.''' | '''HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 27: | Line 27: | ||
[[Category: Watson, N S.]] | [[Category: Watson, N S.]] | ||
[[Category: Young, R J.]] | [[Category: Young, R J.]] | ||
| - | [[Category: 701]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: NA]] | ||
[[Category: acute phase]] | [[Category: acute phase]] | ||
[[Category: blood coagulation]] | [[Category: blood coagulation]] | ||
| Line 48: | Line 45: | ||
[[Category: zymogen]] | [[Category: zymogen]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:05 2008'' |
Revision as of 00:58, 31 March 2008
| |||||||
| , resolution 1.70Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , , , | ||||||
| Activity: | Thrombin, with EC number 3.4.21.5 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.
About this Structure
2JH0 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 03:58:05 2008
Categories: Homo sapiens | Protein complex | Thrombin | Chan, C. | Convery, M A. | Hubbard, J A. | Senger, S. | Shah, G P. | Watson, N S. | Young, R J. | Acute phase | Blood coagulation | Calcium | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Inhibitor | Kringle | Polymorphism | Protease | Protease inhibitor | Serine protease | Serine protease inhibitor | Sulfation | Zymogen
