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| - | | + | #REDIRECT [[6dk3]] This PDB entry is obsolete and replaced by 6dk3 |
| - | ==HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2==
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| - | <StructureSection load='3ou5' size='340' side='right' caption='[[3ou5]], [[Resolution|resolution]] 2.04Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3ou5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2a7v 2a7v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OU5 FirstGlance]. <br>
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| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SHMT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ou5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ou5 OCA], [http://pdbe.org/3ou5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ou5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ou5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ou5 ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Glycine hydroxymethyltransferase]]
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| - | [[Category: Human]]
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| - | [[Category: Arrowsmith, C H]]
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| - | [[Category: Bochkarev, A]]
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| - | [[Category: Dong, A]]
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| - | [[Category: Edwards, A M]]
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| - | [[Category: Loppnau, P]]
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| - | [[Category: Plotnikov, A N]]
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| - | [[Category: Structural genomic]]
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| - | [[Category: Sundstrom, M]]
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| - | [[Category: Wu, H]]
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| - | [[Category: Zeng, H]]
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| - | [[Category: Serine hydroxymethyltransferase 2]]
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| - | [[Category: Sgc]]
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| - | [[Category: Transferase]]
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